Deciphering influence and therapeutic significance of gut microbiota and its metabolites on metabolic diseases and inflammatory bowel disease Clinical Nutrition ESPEN L Carnitine intake and high trimethylamine N oxide plasma levels correlate with low aortic lesions in ApoE transgenic mice expressing CETP Atherosclerosis Cleveland Clinic researchers have discovered a connection between elevated blood levels of TMAO (trimethylamine N oxide)a byproduct of gut bacteria digestion of nutrients found in red meat and other animal productsand a higher Frontiers Acetyl L carnitine ameliorates atherosclerosis in LDLR mice by modulating cholesterol metabolism through SREBP2 dependent cholesterol biosynthesis