Glutathione Redox Control of Asthma: From Molecular Mechanisms to Therapeutic Opportunities Anne M. Fitzpatrick, Dean P. Jones, Lou Ann S. Brown, 2012 Reductive Stress Causes Oxidative Stress: Antioxidants, Oxidative Stress and Reductive Stress Fire In A Bottle The effectiveness of compound X is often dependent on the presence of compounds Y and Z and so on. Endogenous compounds like glutathione get much commercial attention but they do not work Item Scheme showing the enzymatic reactions that catalyze the pyruvate dehydrogenase complex, including pyruvate dehydrogenase activity and diaphorase activity of DLD (A) as well as the glutathione reductase peroxidase activity (B).