Copper, Collagen, and Controversy: Inside the GHK Cu Buzz What is GHK CU (Glycine Histidine Lysine Copper) and how is it used for wound healing? Viral claim says GHK Cu reset nearly 4,000 genes to a younger state and increased collagen production in a preclinical study. This refers to research on GHK Cu, a naturally occurring copper binding peptide that Effects of GHK Cu on MMP and TIMP Expression, Collagen and Elastin Production, and Facial Wrinkle Parameters