Did you know that high doses of paracetamol can be toxic to your liver? Paracetamol, also known as acetaminophen, is a commonly used painkiller that can have harmful effects on the body Figure 1 from Acetaminophen toxicity and 5 oxoproline (pyroglutamic acid): a tale of two cycles, one an ATP depleting futile cycle and the other a useful cycle. Semantic Scholar Acetaminophen metabolism and NAPQI mediated mitochondrial effects Download Scientific Diagram Acetaminophen Toxicity: How Genetic Susceptibility Combines with Environmental Factors