Electrochemical evidences in oxidation of acetaminophen in the presence of glutathione and N acetylcysteine Chemical Communications (RSC Publishing) Can Tylenol (acetaminophen) deplete glutathione levels in the body? Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: If youve felt a sense of confusion this week over the White Houses announcement on Tylenol and autism, as well as some of the unproven medical advice given during that press conference, I highly