Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review Spotty lips. These are labial melanotic macules, kinda like freckles on the lips. They are mostly due to age and sun exposure, but sometimes they run in families and are associated with Pigmented Lesions of the Oral Mucosa Pocket Dentistry Mystery behind labial and oral melanotic macules: Clinical, dermoscopic and pathological aspects of Laugier Hunziker syndrome
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oral melanotic macule black spot on lower lip pictures Peutz-Jeghers syndrome: black spots localized in the perioral area