Studies on the reaction of glutathione and formaldehyde using NMR Organic & Biomolecular Chemistry (RSC Publishing) DOI:10.1039 C0OB00208A Your liver needs time to turn ethanol into acetate. If you drink too fast, that "hangover chemical" (acetaldehyde) piles up and ruins the fun. Drink slow and give your enzymes a break. Acetaldehyde dehydrogenase Wikipedia From aldehyde metabolism to delay aging: targeting ALDH2 as a novel strategy ScienceDirect
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acetaldehyde glutathione Combination of Cysteine and Glutathione Prevents Ethanol-Induced Hangover and Liver Damage by Modulation of Nrf2 Signaling in HepG2 Cells and Mice