Autoregulatory control of mitochondrial glutathione homeostasis Science Molecular Vision: De Donatis, Mol Vis 2010; 16:1025 1033. Figure 1 Hepatic Glutathione Synthesis: The Liver's Antioxidant Powerhouse Glutathione (GSH) is the most abundant intracellular antioxidantand the liver is its primary production site. Through a tightly regulated, ATP dependent pathway, hepatocytes Dual regulation of SLC25A39 by AFG3L2 and iron controls mitochondrial glutathione homeostasis: Molecular Cell
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glutathione homeostasis Glutathione equilibrium (GSH/GSSG) following Gln/Glu homeostasis