For CKD, I'd separate the proven support from the experimental but interesting category. Astragalus root extract is probably the most tried and true natural compound I'd look at first. There's actual human data showing Chronic Kidney Disease Ten Rules for Anaesthesia Consideration Anaesthesia News Glutathione specific gammaglutamylcyclotransferase 1 (CHAC1) increases kidney disease risk by modulating ferroptosis Science Translational Medicine Glutathione vs. NAC: Which Antioxidant Is Best for Your Liver? Life Extension
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glutathione or nac better Metabolic Homeostasis of Amino Acids and Diabetic Kidney Disease