Can you take glutathione without vitamin C? The simple answer: NO! Glutathione will not work without Vitamin C. Glutathione remains in two states, active and inactive. When it's in its active state, The Relationship Between Glutathione and Vitamin C: Can We Take Glutathione Without Vitamin C? Bubs Naturals A Literature Review of Glutathione Therapy in Ameliorating Hepatic Dysfunction in Non Alcoholic Fatty Liver Disease Glutathione Results Timeline: When To Expect Skin Benefits