Glutathione: pharmacological aspects and implications for clinical use Geriatric Care https: pubmed.ncbi.nlm.nih.gov 32463221 # The National Library of Medicine posted : Endogenous Deficiency of Glutathione as the Most Likely Cause of Serious Manifestations and Death in COVID 19 Patients Sirona's Glutathione deficiency can lead to a variety of signs and symptoms that affect your overall health. Here are some common signs to look out for: 1. **Increased Dark Spots** Deficient Glutathione in the Pathophysiology of Mycotoxin Related Illness