G6PD Deficiency Causes Haemolytic Anaemia Glucose 6 phosphate dehydrogenase is an enzyme in the hexose monophosphate shunt that synthesizes NADPH. The NADPH is used to convert oxidized glutathione (GSSG) to reduced glutathione ( Correcting glucose 6 phosphate dehydrogenase deficiency with a small molecule activator Nature Communications Glutathione: Role in Oxidative Nitrosative Stress, Antioxidant Defense, and Treatments Raj Rai 2021 ChemistrySelect Wiley Online Library Glutathione is such a critical soldier in our line of defense that our bodies make it themselves. We even have mechanisms that recycle and reuse it. But what happens when our toxic