One Juul pod contains the equivalent nicotine of 20 cigarettes a highly addictive amount. Today, some e cigs can contain more nicotine than *200 cigarettes.* Join us in sending a message to How Many Puffs of Vape are Equal to a Cigarette? EDGE Vaping 1 standard vape pod does not directly equal 20 packs of cigarettes in terms of nicotine content, but it can contain nicotine equivalent to a pack of cigarettes. A JUUL pod, for Your Guide to JUUL Pods and How Long They Last