Smoking Vape Side Effects Smoking Vs. Vaping: Is One Really Safer Than The Other Smoking Vape Pipe And Tobacco Can vaping cause cancer? The evidence suggests it might. The Washington Post Can Vaping Cause a Headache? Vaping delivers heated chemicals directly into the lungs. Unlike air, vape aerosols contain fine particles, nicotine, heavy metals, and flavoring compounds that were never designed to be inhaled. Once inside the chest,