Discover How Many Cigarettes in a Vape? Find Out Here! Say no to vaping. 10 15 vape puffs are roughly equivalent to one cigarette. We want to encourage and support families to have open and engaging conversations with young people to Vaping may seem harmless, but the reality is far from it. A single disposable vape can expose you to nicotine levels equal to multiple cigarettes, making it highly addictive and harmful. It's 1 vape vs. 1 pack of cigarettes