Vape vs Cigarette Nicotine: How Many 5% Vape Puffs Equal One Cig? 1 vape = 50 cigarettes Many vapes have 50mg nicotine which is equivalent to roughly 50 cigarettes. * Depending on the size of the vape and nicotine strength, it can be What's the Difference Between E Cigarettes and Vapes? Grow Strong KC The nicotine content of many 2ml nicotine pods for multi pod devices is equivalent to a pack of 20 cigarettes. If you don't smoke, don't vape. And if you are smoking