VAP Bundle Ventilator Associated Pneumonia Ventilator Associated Pneumonia ( VAP) is a lung infection that occurs in patients who are on mechanical ventilation for more than 48 hours. A VAP bundle is a set of Importance of Infection Prevention from VAP and Use of Care Bundle Checklist Ventilator Associated Pneumonia: Treatment & Prevention Study.com VAP, VAC, IVAC and Ventilator Associated Events: The Need for Objectivity for Surveillance